Quarterback Ryan Tannehill was injured on the Miami Dolphins' second possession of the game. The Indianapolis Colts lost cornerback Vontae Davis to a sprained left knee on the Tennessee Titans' opening drive.
At least Tannehill and Davis each got to celebrate a victory - Kansas City quarterback Brady Quinn got hurt in the first half of the Chiefs' 26-16 loss to the Oakland Raiders.
Miami turned to Matt Moore after Tannehill injured his left knee and quadriceps muscle on a sack by Calvin Pace, and Moore threw a touchdown pass to Anthony Fasano to help the Dolphins beat the New York Jets 30-9 on Sunday for their third straight victory.
Coach Joe Philbin had no immediate word on the severity of the injury, saying Tannehill would be evaluated after the Dolphins arrived home. Moore filled in nicely, finishing 11 of 19 for 131 yards after Tannehill was 2 of 5 for 18 yards.
Tannehill was drafted with the eighth overall pick, which made him the first quarterback taken in the opening round by the Dolphins since Dan Marino in 1983. He beat out Moore for the starting job during training camp.
Davis went down defending Chris Johnson on a run during Indianapolis' 19-13 overtime victory at Tennessee. He stayed on the field for a couple minutes before walking off. He was replaced by Cassius Vaughn.
Colts tight end Coby Fleenor hurt a shoulder in the first half and had one pass thrown at him in the second half.
Quinn was hit hard on a sack by Rolando McClain on the Chiefs' third possession, and then took another shot when he threw an interception off his back foot. Matt Cassel came into the game for the Chiefs' next series.
The team said Quinn had a ``head injury.'' He was starting in place of Cassel, who was benched after a weak start to the year.
Dallas linebacker Dan Connor strained his neck in the second quarter of the Cowboys' 29-24 loss to the New York Giants. He remained down on the ground at the end of a play when the Giants fumbled, and did not play in the second half.
Connor started in place of injured leading tackler Sean Lee, who was put on injured reserve this week because of a big toe injury sustained in last week's win at Carolina that will require season-ending surgery. Lee was on the sideline in crutches Sunday.
The Giants also lost a starting linebacker when Chase Blackburn was knocked out in the second half because of a left hamstring injury.